CPRI CPRI and COBRE Publications
Publications
CPRI Representative Publications
- Henderson IM, Zeng F, Bhuiyan NH, Luo D, Martinez M, Smoake J, Bi F, Perera C, Johnson D, Prisinzano TE, Wang W, Uhl GR. Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development. Biochem Pharmacol. 2022 Jan;195:114868. doi: 10.1016/j.bcp.2021.114868. Epub 2021 Dec 2. PMID: 34863978; PMCID: PMC9248268.
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Hedrick SL, Luo D, Kaska S, Niloy KK, Jackson K, Sarma R, Horn J, Baynard C, Leggas M, Butelman ER, Kreek MJ, Prisinzano TE. Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent. J Biomed Sci. 2021 Sep 9;28(1):62. doi: 10.1186/s12929-021-00758-y. PMID: 34503531; PMCID: PMC8427951.
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Zhou S, Zheng F, Zhan CG. Clinical data mining reveals analgesic effects of lapatinib in cancer patients. Sci Rep. 2021 Feb 11;11(1):3528. doi: 10.1038/s41598-021-82318-w. PMID: 33574423; PMCID: PMC7878815.
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Clinger JA, Wang X, Cai W, Zhu Y, Miller MD, Zhan CG, Van Lanen SG, Thorson JS, Phillips GN Jr. The crystal structure of AbsH3: A putative flavin adenine dinucleotide-dependent reductase in the abyssomicin biosynthesis pathway. Proteins. 2021 Jan;89(1):132-137. doi: 10.1002/prot.25994. Epub 2020 Oct 21. PMID: 32852843; PMCID: PMC7910320.
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Denny L, Al Abadey A, Robichon K, Templeton N, Prisinzano TE, Kivell BM, La Flamme AC. Nalfurafine reduces neuroinflammation and drives remyelination in models of CNS demyelinating disease. Clin Transl Immunology. 2021 Jan 17;10(1):e1234. doi: 10.1002/cti2.1234. PMID: 33489124; PMCID: PMC7811802.
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Ye Q, Zhang Y, Cao Y, Wang X, Guo Y, Chen J, Horn J, Ponomareva LV, Chaiswing L, Shaaban KA, Wei Q, Anderson BD, St Clair DK, Zhu H, Leggas M, Thorson JS, She QB. Frenolicin B targets peroxiredoxin 1 and glutaredoxin 3 to trigger ROS/4E-BP1-mediated antitumor effects. Cell Chemical Biology. 2019; 26(3):366-377. PMCID: PMC6557261
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Mitra P, Eckenrode JM, Mandal A, Jha AK, Salem SM, Leggas M, Rohr J. Development of mithramycin analogues with increased selectivity toward ETS transcription factor expressing cancers. Journal of Medicinal Chemistry. 2018; 61(17):8001-8016. PMCID: PMC6888919
COBRE Project Representative Publications
- Ofori S, Gukathasan S, Awuah S (2021). Gold-Based Pharmacophore Inhibits Intracellular MYC Protein. Chemistry 27(12):4168-4175. PMID: 33275307 DOI: 10.1002/chem.202004962
- Boyd JD, Grady ME (2020). The effect of surface roughness on laser-induced stress wave propagation. Applied Physics Letters, 117, 121601. https://doi.org/10.1063/5.0021021
- Pitts MG, Nardo D, Isom CM, Venditto VJ (2020). Autoantibody Responses to Apolipoprotein A-I Are Not Diet- or Sex-Linked in C57BL/6 Mice. Immunohorizons 4(8):455-463. PMCID: PMC7646948
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Inquiries
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Funding Acknowledgment Statement
This work was supported by the Center for Pharmaceutical Research and Innovation (CPRI, NIH P20 GM130456) and the National Center for Advancing Translational Sciences (UL1 TR001998).