CPRI facilitates the development and implementation of unique tools and reagents to support translational research and drug discovery and development. These include commercially-sourced and UK-exclusive compound libraries, alternative animal models, assays and computational tools.
In collaboration with UK investigators, CPRI is exploring a number of alternative in vivo models for new applications in fundamental research and/or preclinical probe/lead discovery/development.
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The Translational Core supports the development and implementation of a diverse range of biochemical, cell-based and whole animal assays for probe/lead discovery/development projects.
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CPRI houses a range of commercially-sourced and UK-exclusive compound collections to support collaborative screening projects conducted in the Translational Core or via select external screening center partnerships.
The Computational Core provides state-of-the-art molecular modeling, simulation, and computational tools to support collaborative translational research and probe/lead discovery/development projects.
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The CPRI seeks to develop innovative research partnerships with UK investigators. For more information and to request services, please contact us.
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This work was supported by the Center for Pharmaceutical Research and Innovation (CPRI, NIH P20 GM130456) and the National Center for Advancing Translational Sciences (UL1 TR001998).
