The Bio Core commonly engages in assay development/validation/implementation, virtual and wet bench screening, hit identification, and hit/lead candidate validation studies. Virtual and wet bench screening activities in the core employ both commercially available libraries and our exclusive UK-based collections (see Compound Collections). The CTCB Bio Core works closely with the CTCB Chem Core for medchem-guided probe/lead prioritization. The Bio Core is directed by Professor Steven Van Lanen and co-directed by Professor Chang-Guo Zhan.