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COBRE Projects, Pilots, & Scholars to Date


COBRE-Affiliated Funding to Date


COBRE Participating Departments

A Commitment to Research Mentorship, Scientific Cross-Cultivation and Innovative Team Science

As a Center of Biomedical Research Excellence (COBRE, NIH P20 GM130456), the mission of the Center for Pharmaceutical Research and Innovation (CPRI) COBRE for Translational Chemical Biology is to support junior faculty career development, advance impactful translational chemical biology research/tools, and stimulate transdisciplinary collaboration, research innovation and early translation. Within this context, the COBRE synergizes with and builds on CPRI's central mission as a primary lead discovery and development resource for the University of Kentucky and the Commonwealth.

COBRE Projects & Pilots

CPRI's COBRE for Translational Chemical Biology supports innovative junior investigator projects and pilots by providing both research funding and mentorship.


CPRI's COBRE for Translational Chemical Biology is lead by an experienced Executive Committee and world-class External Advisory Committee.

CPRI Research Cores & Resources

The COBRE for Translational Chemical Biology augments and leverages CPRI core services, state-of-the-art facilities, and unique expertise to facilitate translational research.


COBRE Project and Pilot Leaders receive awards

Former COBRE Project Leader, Dr. Martha Grady, and former COBRE Pilot Project Leader, Dr. Yosra Helmy, among 4 professors to receive Excellent Undergraduate Research Mentor Awards

Seeking Cures in Kentucky Coal Mines

Read more about how natural products-based lead to discovery in our Newsweek feature.


NIH Awards $11.2 Million for Pharmaceutical Research and Innovation Center at UK

The University of Kentucky was awarded a prestigious Centers of Biomedical Research Excellence (COBRE) grant to study translational chemical biology from the National Institutes of General Medical Sciences, part of the National Institutes of Health.


The CPRI seeks to develop innovative research partnerships with UK investigators. For more information and to request services, please contact us.

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Funding Acknowledgment Statement

This work was supported by the Center for Pharmaceutical Research and Innovation (CPRI, NIH P20 GM130456) and the National Center for Advancing Translational Sciences (UL1 TR001998).

We wish to remember and honor those who inhabited this Commonwealth before the arrival of the Europeans. Briefly occupying these lands were the Osage, Wyndott tribe, and Miami peoples. The Adena and Hopewell peoples, who are recognized by the naming of the time period in which they resided here, were here more permanently. Some of their mounds remain in the Lexington area, including at UK’s Adena Park.

In more recent years, the Cherokee occupied southeast Kentucky, the Yuchi southwest Kentucky, the Chickasaw extreme western Kentucky and the Shawnee central Kentucky including what is now the city of Lexington. The Shawnee left when colonization pushed through the Appalachian Mountains. Lower Shawnee Town ceremonial grounds are still visible in Greenup County.

We honor the first inhabitants who were here, respect their culture, and acknowledge the presence of their descendants who are here today in all walks of life including fellow pharmacists and healthcare professionals.