Skip to main
Skip to main
University-wide Navigation
Jim Pauly uky headshot
Categories
All Faculty
Pharmaceutical Sciences Dept.
Location
B451 Biomedical/Biological Sciences Research Building
Phone
859-23-8164
Email
jim.pauly@uky.edu

Dr. Pauly's research interests are primarily focused on the neurobiological actions of nicotine. The CNS nicotinic cholinergic system is studied using techniques that include quantitative receptor autoradiography, quantitative in situ hybridization histochemistry, ion flux assays and behavioral analyses. Dr. Pauly's lab is currently studying 1) the effects of prenatal nicotine exposure on brain development 2) the actions of steroid hormones (adrenal and ovarian) on the number and functional status of brain nicotinic receptor subtypes 3) the role of alpha 7 nicotinic receptors in regulating responsiveness to nicotine and 4) the brain nicotinic system in neurodegenerative conditions such as Alzheimer's and Parkinson's Disease. Dr. Pauly is also interested in the use of novel radioligands for the histochemical localization of receptor subtypes in the CNS as well as peripheral tissues such as the lung and heart.

PUBLICATIONS

Interests

Education & Appointments

Education:

  • PhD Array
  • MS Western Kentucky University
  • BS Northern Kentucky University

Position:

  • Professor, Department of Pharmaceutical Sciences