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All College of Pharmacy NMR users wanting to use TopSpin/protein dynamics, VNMR, nmrPipe and SPARKY software for themselves – off-line data processing station is available in the basement in front of the PharmNMR room.

Our facilities are available for use for the following users:

  • UK College of Pharmacy researchers
  • University of Kentucky researchers
  • Researchers from any Kentucky university
  • External researchers/customers from industry (contact Center Director)

NMR Data Analyses

  • Assistance with basic interpretation of NMR spectra of small molecules
  • Spectral assignments for small molecule (1D and 2D NMR)
  • Spectral assignments for biomolecules (1D, 2D, and 3D NMR data)
  • Structure calculation for peptides and proteins (SPARKY and CYANA)
  • NMR relaxation data (T1, T2, heteronuclear-NOE,)
  • Protein-ligand interaction
  • Binding constant calculations

Preparation & Processing

  • A large range of deuterated solvents will be provided for external users.
  • Quality NMR tubes will be used for external samples
  • Appropriate buffer solution for biomolecular NMR sample with specific pH can be prepared
  • Tips on how to process your spectra to get the best results
  • Data processing of Varian data using Topspin or nmrPipe
  • TopSpin plot editor

We wish to remember and honor those who inhabited this Commonwealth before the arrival of the Europeans. Briefly occupying these lands were the Osage, Wyndott tribe, and Miami peoples. The Adena and Hopewell peoples, who are recognized by the naming of the time period in which they resided here, were here more permanently. Some of their mounds remain in the Lexington area, including at UK’s Adena Park.

In more recent years, the Cherokee occupied southeast Kentucky, the Yuchi southwest Kentucky, the Chickasaw extreme western Kentucky and the Shawnee central Kentucky including what is now the city of Lexington. The Shawnee left when colonization pushed through the Appalachian Mountains. Lower Shawnee Town ceremonial grounds are still visible in Greenup County.

We honor the first inhabitants who were here, respect their culture, and acknowledge the presence of their descendants who are here today in all walks of life including fellow pharmacists and healthcare professionals.