CPRI facilitates the development and implementation of unique tools and reagents to support translational research and drug discovery and development. These include commercially-sourced and UK-exclusive compound libraries, alternative animal models, assays and computational tools.
CPRI Tools and Reagents
In Vivo Models
In collaboration with UK investigators, CPRI is exploring a number of alternative in vivo models for new applications in fundamental research and/or preclinical probe/lead discovery/development.
Assays
The Translational Core supports the development and implementation of a diverse range of biochemical, cell-based and whole animal assays for probe/lead discovery/development projects.
Compound and Natural Products Libraries
CPRI houses a range of commercially-sourced and UK-exclusive compound collections to support collaborative screening projects conducted in the Translational Core or via select external screening center partnerships.
Computational Tools
The Computational Core provides state-of-the-art molecular modeling, simulation, and computational tools to support collaborative translational research and probe/lead discovery/development projects.
Inquiries
The CPRI seeks to develop innovative research partnerships with UK investigators. For more information and to request services, please contact us.
Funding Acknowledgment Statement
This work was supported by the Center for Pharmaceutical Research and Innovation (CPRI, NIH P20 GM130456) and the National Center for Advancing Translational Sciences (UL1 TR001998).
We wish to remember and honor those who inhabited this Commonwealth before the arrival of the Europeans. Briefly occupying these lands were the Osage, Wyndott tribe, and Miami peoples. The Adena and Hopewell peoples, who are recognized by the naming of the time period in which they resided here, were here more permanently. Some of their mounds remain in the Lexington area, including at UK’s Adena Park.
In more recent years, the Cherokee occupied southeast Kentucky, the Yuchi southwest Kentucky, the Chickasaw extreme western Kentucky and the Shawnee central Kentucky including what is now the city of Lexington. The Shawnee left when colonization pushed through the Appalachian Mountains. Lower Shawnee Town ceremonial grounds are still visible in Greenup County.
We honor the first inhabitants who were here, respect their culture, and acknowledge the presence of their descendants who are here today in all walks of life including fellow pharmacists and healthcare professionals.