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A Commitment to Positive Impact Throughout the Commonwealth

As a Center of Biomedical Research Excellence (COBRE; NIH P20 GM130456), our mission is to support junior faculty career development, advance impactful translational chemical biology research/tools, and stimulate transdisciplinary collaboration, research innovation and early translation. CPRI serves as a catalyst for lead discovery and development with a strategic focus on addressing major health challenges in the Commonwealth and enabling pharmaceutical commercialization and economic development opportunities in Kentucky.

Research Cores and Resources

The CPRI provides core services, state-of-the-art facilities, and unique expertise to facilitate translational research.

CPRI and COBRE Projects

CPRI works with many talented UK investigators and the network of world-class UK Centers focused on major health disparities in the Commonwealth.


Our scientists are the intellectual engine of CPRI and innovators in team-driven probe/lead discovery, development, and commercialization.


Seeking Cures in Kentucky Coal Mines

Read more about how natural products-based lead to discovery in our Newsweek feature.


NIH Awards $11.2 Million for Pharmaceutical Research and Innovation Center at UK

The University of Kentucky was awarded a prestigious Centers of Biomedical Research Excellence (COBRE) grant to study translational chemical biology from the National Institutes of General Medical Sciences, part of the National Institutes of Health.


The CPRI seeks to develop innovative research partnerships with UK investigators. For more information and to request services, please contact us.

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Recommended CPRI Acknowledgment

This work was supported by the Center for Pharmaceutical Research and Innovation (CPRI, NIH P20 GM130456) and the National Center for Advancing Translational Sciences (UL1 TR001998).

We respectfully acknowledge the Elders and Traditional Owners of the land on which our building stands, which is the traditional territory of the Osage, Shawnee, Cherokee, Adena, and Hopewell peoples.