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All Faculty
Pharmaceutical Sciences Dept.
Lee T. Todd, Jr. Bldg, Room 323

Dr. Leggas joined the University of Kentucky College of Pharmacy in 2004 and his research efforts have focused on preclinical and clinical pharmacology and translational projects to develop drugs or repurpose clinically approved ones. Currently, Dr. Leggas' research is supported by funding from the NIH and the Department of Defense.

His laboratory emphasizes the use of molecular and cellular biology along with classical pharmacology tools like pharmacokinetic and pharmacodynamic experiments, modeling and simulation to rapidly and rationally accelerate drug development.

A major research focus of the Leggas laboratory is placed on discovering and developing drug that inhibit oncogenic transcription factors.

Dr. Leggas is also serving as the leader for the Translational studies core in the Center for Pharmaceutical Research and Innovation, which facilitates preclinical and clinical drug development efforts across Kentucky.



  • Clinical Pharmacology and Experimental Therapeutics and Anticancer Drugs
  • Modeling and Simulation
  • Pharmacokinetics and pharmacodynamics
  • Targeting transcription factors
  • Gastrointestinal Physiology, Muscle Physiology, Bone Physiology, Pharmacokinetics/Pharmacodynamics

Education & Appointments


  • PhD Univ Of Tennessee-Medical
  • MS Univ Of Tennessee-Medical
  • BS Union University


  • Associate Professor, Department of Pharmaceutical Sciences

We respectfully acknowledge the Elders and Traditional Owners of the land on which our building stands, which is the traditional territory of the Osage, Shawnee, Cherokee, Adena, and Hopewell peoples.