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Blocking Cancer—Scientists Find New Way to Combat Disease

New findings published in Nature Chemical Biology show promise for finding new solutions to treat lung cancer and other deadly diseases. Kentucky continues to lead the nation in incidence and death rates from lung cancer, and the University of Kentucky College of Pharmacy is committed to reducing these numbers.

Monthly Research Publication Highlight reveals new insight into the impact of pneumonia-causing pathogens on host defense and chronic lung disease

The UK College of Pharmacy Research Publication Highlight for April 2017 was published in Immunobiology and is titled, “Pneumocystis infection alters the activation state of pulmonary macrophages”.

The College of Pharmacy Monthly Research Publication Highlight compares the efficacy of antibiotics in patients with infections in intensive care units

The UK College of Pharmacy Research Publication Highlight for March, 2017 is titled “Comparison of ß-lactam plus aminoglycoside versus ß-lactam plus fluoroquinolone empirical therapy in serious nosocomial infections due to Gram-negative bacilli” and was published in the Journal of Chemotherapy.

Monthly Research Publication Highlight details a novel method to quantify the intracellular uptake and trafficking of gene therapy nanoparticles

The UK College of Pharmacy Research Publication Highlight for February, 2017 is titled “Rapid and facile quantitation of polyplex endocytic trafficking” and was published in the The Journal of Controlled Release.

Monthly Research Publication Highlight reports on one of the many challenges in the manufacturing of pharmaceuticals.

The UK College of Pharmacy Research Publication Highlight for January, 2017 was published in the Journal of Pharmaceutical Sciences and is titled “Characterization of Synthesized and Commercial Forms of Magnesium Stearate Using Differential Scanning Calorimetry, Thermogravimetric Analysis, Powder X-Ray Diffraction, and Solid-State NMR Spectroscopy”.

Research Publication Highlight: Rates of Neonatal Abstinence Syndrome Amid Efforts to Combat the Opioid Abuse Epidemic

The College of Pharmacy Monthly Research Publication Highlight documents the rise in the number of newborns beginning life facing drug withdrawal in the nation, and particularly in Kentucky. The UK College of Pharmacy Research Publication Highlight for November 2016 was published in the Journal of the American Medical Association -Pediatrics and is titled “Rates of Neonatal Abstinence Syndrome Amid Efforts to Combat the Opioid Abuse Epidemic”.

APhA-ASP Regional Awards

American Pharmacists Association - Academy of Student Pharmacists (APhA-ASP) is a national organization dedicated to promoting student growth, improved patient care, and the profession of pharmacy. In an effort to enhance patient care, APhA-ASP has established a number of national patient care and community service projects aimed to educate and screen for various disease states ranging from diabetes and heart disease to prescription medication abuse and misuse.

Monthly Research Publication Highlight details the discovery of new enzyme inhibitors that may be useful in the future treatment of tuberculosis.

The UK College of Pharmacy Research Publication Highlight for October, 2016 was published in the ACS Chemical Biology and is titled “Discovery of Allosteric and Selective Inhibitors of Inorganic Pyrophosphatase from Mycobacterium tuberculosis”.

Monthly Research Publication Highlight details a role for inflammatory signaling lipids in cardiovascular diseases

The UK College of Pharmacy Research Publication Highlight for September, 2016 was published in the Journal of Cardiovascular Pharmacology and is titled “Microsomal Prostaglandin E Synthase-1 Expression by Aortic Smooth Muscle Cells Attenuates the Differentiated Phenotype”. The project was conducted in the laboratory of Dr. Charles Loftin and features the dissertation research of Dr. Oreoluwa Adedoyin, a recent graduate of the Pharmaceutical Sciences PhD program in the College of Pharmacy.

Research Highlight reveals the challenge of treating chronic respiratory infections in patients with Cystic Fibrosis.

The UK College of Pharmacy Research Publication Highlight for July, 2016 is to be published in the Journal of Cystic Fibrosis and is titled “Optimizing beta-lactam pharmacodynamics against Pseudomonas aeruginosa in adult cystic fibrosis patients”.

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We wish to remember and honor those who inhabited this Commonwealth before the arrival of the Europeans. Briefly occupying these lands were the Osage, Wyndott tribe, and Miami peoples. The Adena and Hopewell peoples, who are recognized by the naming of the time period in which they resided here, were here more permanently. Some of their mounds remain in the Lexington area, including at UK’s Adena Park.

In more recent years, the Cherokee occupied southeast Kentucky, the Yuchi southwest Kentucky, the Chickasaw extreme western Kentucky and the Shawnee central Kentucky including what is now the city of Lexington. The Shawnee left when colonization pushed through the Appalachian Mountains. Lower Shawnee Town ceremonial grounds are still visible in Greenup County.

We honor the first inhabitants who were here, respect their culture, and acknowledge the presence of their descendants who are here today in all walks of life including fellow pharmacists and healthcare professionals.