Garneau-Tsodikova Laboratory

Our Mission

The fundamental goal of our research is to understand and exploit the enzymes involved in natural product biosynthesis and bacterial resistance with the ultimate objective of developing novel biologically active compounds that target infectious diseases and malignant tumors. We are especially interested in two classes of compounds: the aminoglycoside antibiotics and the nonribosomal peptides. We focus on lung diseases (Tuberculosis), cancer, and Alzheimer's Disease. The research in our laboratory lies at the interface of biology, organic chemistry, and medicine. Tools and strategies from molecular biology, biochemistry, microbiology, as well as synthetic organic and medicinal chemistry are key to our work.

Our Research

Our Achievements


Publications in 2018




Read about our work in the community.

A computer and a term paper


For a complete list of our publications, book chapters and articles.