Dr. Younsoo Bae is a pharmaceutical scientist with expertise in drug and gene delivery. Dr. Bae received his PhD in materials science and engineering from University of Tokyo in 2005, and completed postdoctoral training at the School of Pharmacy, University of Wisconsin-Madison. Dr. Bae joined the department of pharmaceutical sciences, College of Pharmacy, University of Kentucky, in 2008.
Rheiner S, Bae Younsoo. (2016). Increased poly(ethylene glycol) density decreases transfection efficacy of sirna/poly(ethylene imine) complexes.Bioengineering, 3(4), 454-467.
Yarana C, Carroll D, Chaiswing L, Zhao Y, Noel T, Alstotte M, Chen J, Zhu H, Bae Younsoo, Dressler E, Moscow J, Butterfiled A, St Clair D. (2016). Alteration of circulating extracellular vesicle protein contents is a fingerprint of chemotherapy-induced tissue damage.Clin Cancer Res, Submitted.
Park J E, -E Chun S, Reichel D, Min J S, -C Lee S, Han S, Ryoo G, Oh Y, -H Park S, -M Ryu H, Kim K B, -Y Lee H, Bae S K, Bae Younsoo, Lee W. (2016). Polymer micelle formulation for the proteasome inhibitor drug carfilzomib: Anticancer efficacy and pharmacokinetic studies in mice.PlosOne, Submitted.
Reichel D, Bae Younsoo. (2016). Comparison of dialysis- and solvatofluorochromism-based methods to determine drug release rates from polymer nanoassemblies.Pharm Res, Published Online.
Dickerson M, Howerton B, Bae Younsoo, Glazer Edith (Phoebe) Caroline. (2016). Light-sensitive ruthenium complex-loaded cross-linked polymeric nanoassemblies for the treatment of cancer.J Mater Chem B Mater Biol Med, 4(394-408),
Curtis L T, Rychahou Piotr Grigorievich, Bae Younsoo, Frieboes H B. (2016). A computational/experimental assessment of antitumor activity of polymer nanoassemblies for ph-controlled drug delivery to primary and metastatic tumors.Pharm. Res., 33, 2552–2564.
Reichel D, Lee Min-Young, Lee Wooin, Kim Kyung Bo, Bae Younsoo. (2016). Tethered polymer nanoassemblies for sustained carfilzomib release and prolonged suppression of proteasome activity.Therapeutic delivery, 7(10), 665-681.
Dan M, Bae Younsoo, Pittman Thomas A, Yokel Robert A. (2015). Alternating Magnetic Field-Induced Hyperthermia Increases Iron Oxide Nanoparticle Cell Association/Uptake and Flux in Blood-Brain Barrier Models.Pharmaceutical research, 32(5), 1615-1625.
Reichel D, Rychahou Piotr Grigorievich, Bae Younsoo. (2015). Polymer nanoassemblies with solvato- and halo-fluorochromic properties for real-time monitoring of drug release and pH-enhanced ex vivo imaging of metastatic tumors.Ther Delivery, 6(1221-1237),