Dr. Bradley Anderson
Dr. Bradley Anderson

Professor

Dr. Brad Anderson is a Professor in Pharmaceutical Sciences at the College of Pharmacy, University of Kentucky. Dr. Anderson received his M.S. and Ph.D. in Pharmaceutical Chemistry from the University of Kansas in 1978. He spent the next five years as a research scientist at The Upjohn Co. for 5 years before joining the University of Utah in 1983 as an Associate Professor in Pharmaceutics and Pharmaceutical Chemistry. Dr. Anderson relocated to the University of Kentucky in 2000 where he served as Chair of the Pharmaceutical Sciences department until 2003 and as Interim Chair in 2012-13. He is a Charter Member of the AAPS and an AAPS Fellow. He has received several awards throughout his career including the Pfizer Young Investigator Award (1985), the Meritorious Manuscript Award from Pharm. Res. (1990), the Outstanding Paper Award in J. Controlled Release (1992), the Ebert Prize for the best paper in J. Pharm. Sci. (1998), the University of Utah Distinguished Research Award (1999), the AAPS Dale E. Wurster Research Award in Pharmaceutics (2012), and the AAPS Outstanding Educator Award (2016). Anderson serves on several editorial advisory boards and is an Editor for J. Pharm. Sci. He holds several patents in prodrug design and drug delivery system design and has approximately 160 publications in drug solubilization and stabilization, prodrug design and drug targeting for the treatment of cancer and AIDS, lipid bilayer transport and liposomal drug delivery, and computational methods for predicting membrane transport and drug formulation properties. His current research interests include lipid bilayer membrane transport, controlled drug-delivery to solid tumors using nanotechnology, chemical stability in amorphous solid-state formulations, and molecular dynamics simulations to explore the properties of drugs in amorphous formulations.

Recent Publications

  • Anderson Bradley D, Xiang Tian-Xiang. (2016). Molecular Dynamics Simulations of Amorphous Systems. Wiley,
  • Yuan X, Xiang T X, Anderson Bradley D, Munson Eric Jon. (2015). Hydrogen Bonding Interactions in Amorphous Indomethacin and Its Amorphous Solid Dispersions with Poly(vinylpyrrolidone) and Poly(vinylpyrrolidone-co-vinyl acetate) Studied Using (13)C Solid-State NMR. Molecular pharmaceutics, 12(12), 4518-28.
  • Fugit Kyle, Xiang T X, du Choi H, Kangarlou S, Csuhai E, Bummer Paul M, Anderson Bradley D. (2015). Mechanistic model and analysis of doxorubicin release from liposomal formulations. Journal of controlled release : official journal of the Controlled Release Society, 217, 82-91.
  • Jyoti A, Fugit Kyle, Sethi P, McGarry Ronald Charles, Anderson Bradley D, Upreti Meenakshi. (2015). An in vitro assessment of liposomal topotecan simulating metronomic chemotherapy in combination with radiation in tumor-endothelial spheroids. Scientific reports, 5, 15236.
  • Patel D D, Anderson Bradley D. (2015). Adsorption of Polyvinylpyrrolidone and its Impact on Maintenance of Aqueous Supersaturation of Indomethacin via Crystal Growth Inhibition. Journal of pharmaceutical sciences, 104(9), 2923-33.
  • Csuhai E, Kangarlou S, Xiang T X, Ponta A, Bummer Paul M, Choi D, Anderson Bradley D. (2015). Determination of key parameters for a mechanism-based model to predict Doxorubicin release from actively loaded liposomes. Journal of pharmaceutical sciences, 104(3), 1087-98.
  • Fugit Kyle, Jyoti A, Upreti Meenakshi, Anderson Bradley D. (2015). Insights into accelerated liposomal release of topotecan in plasma monitored by a non-invasive fluorescence spectroscopic method. Journal of controlled release : official journal of the Controlled Release Society, 197, 10-9.
  • Ponta A, Fugit Kyle, Anderson Bradley D, Bae Younsoo. (2015). Release, partitioning, and conjugation stability of doxorubicin in polymer micelles determined by mechanistic modeling. Pharm Res, 32(5), 1752-63.
  • Anderson Bradley D. (2015). “The State of Water and Its Impact in Pharmaceutical Systems: Lipid-Based Drug Delivery Systems and Amorphous Solids”. Springer,
  • Xiang T X, Anderson Bradley D. (2014). Molecular dynamics simulation of amorphous hydroxypropyl-methylcellulose acetate succinate (HPMCAS): polymer model development, water distribution, and plasticization. Molecular pharmaceutics, 11(7), 2400-11.